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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDRG2
All Species:
28.18
Human Site:
Y217
Identified Species:
62
UniProt:
Q9UN36
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN36
NP_057334.1
371
40798
Y217
N
S
E
L
I
Q
K
Y
R
N
I
I
T
H
A
Chimpanzee
Pan troglodytes
A5A6K6
357
39342
Y203
N
S
E
L
I
Q
K
Y
R
N
I
I
T
H
A
Rhesus Macaque
Macaca mulatta
XP_001095407
328
35491
A181
Y
R
N
I
I
T
H
A
P
N
L
D
N
I
E
Dog
Lupus familis
XP_851185
371
40699
Y217
N
S
E
L
I
Q
K
Y
R
N
I
I
T
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYG0
371
40771
Y217
N
S
E
L
I
Q
K
Y
R
G
I
I
Q
H
A
Rat
Rattus norvegicus
Q8VBU2
371
40761
Y217
N
S
E
L
I
Q
K
Y
R
S
L
I
T
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516771
363
39956
Y212
S
S
E
L
V
Q
R
Y
R
E
V
I
V
H
A
Chicken
Gallus gallus
XP_001231665
515
55908
Y350
N
T
E
L
V
Q
S
Y
R
Q
Q
I
G
S
V
Frog
Xenopus laevis
Q7ZY73
360
39367
Y213
N
S
D
V
V
R
Q
Y
K
A
S
I
S
N
S
Zebra Danio
Brachydanio rerio
Q5PR98
368
40449
H217
N
T
E
L
I
Q
T
H
R
E
R
I
T
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02485
325
35573
G178
Y
L
L
A
H
K
F
G
G
E
S
K
S
R
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
80.3
96.5
N.A.
95.6
95.9
N.A.
84.3
45.6
72.7
69.2
N.A.
N.A.
N.A.
24.7
N.A.
Protein Similarity:
100
95.9
83
98.1
N.A.
98.1
98.9
N.A.
90.3
57.4
85.4
84
N.A.
N.A.
N.A.
43.9
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
86.6
86.6
N.A.
60
46.6
26.6
60
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
86.6
100
N.A.
86.6
60
86.6
73.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
64
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
73
0
0
0
0
0
0
28
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
10
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
10
10
0
0
0
0
0
55
0
% H
% Ile:
0
0
0
10
64
0
0
0
0
0
37
82
0
10
0
% I
% Lys:
0
0
0
0
0
10
46
0
10
0
0
10
0
10
0
% K
% Leu:
0
10
10
73
0
0
0
0
0
0
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
73
0
10
0
0
0
0
0
0
37
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
73
10
0
0
10
10
0
10
0
10
% Q
% Arg:
0
10
0
0
0
10
10
0
73
0
10
0
0
10
0
% R
% Ser:
10
64
0
0
0
0
10
0
0
10
19
0
19
10
10
% S
% Thr:
0
19
0
0
0
10
10
0
0
0
0
0
46
0
0
% T
% Val:
0
0
0
10
28
0
0
0
0
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _